EXCAVATE-HT Documentation ========================= EXCAVATE-HT (EXtraction of Common Allelic VAriants for Targeted Editing in High-Throughput) is a Python-based bioinformatic pipeline to mine population and personalised variant data to identify genomic loci targetable for CRISPR-based allele-specific editing and create single and dual-gRNA libraries to enable high-throughput screens of these edits. .. toctree:: :maxdepth: 2 :caption: Contents how_it_works installation parameters examples api_reference contributing Indices and tables ================== * :ref:`genindex` * :ref:`modindex` * :ref:`search`